Epimerase activity of the human 11 β-hydroxysteroid dehydrogenase type 1 on 7-hydroxylated C₁₉-steroidsHENNEBERT, Olivier; MONTES, Matthieu; FAVRE-REGUILLON, Alain et al.Journal of steroid biochemistry and molecular biology. 2009, Vol 114, Num 1-2, pp 57-63, issn 0960-0760, 7 p.Conference Paper

Development of a High-Throughput Cell-Based Assay for 11β-Hydroxysteroid Dehydrogenase Type 1 Using BacMam TechnologyWANG, Da-Yuan; LU, Quinn; WALSH, Stacey L et al.Molecular biotechnology. 2008, Vol 39, Num 2, pp 127-134, issn 1073-6085, 8 p.Conference Paper

Expression of genes related to glucocorticoid action in human subcutaneous and omental adipose tissueVEILLEUX, Alain; LABERGE, Philippe Y; MORENCY, Jacques et al.Journal of steroid biochemistry and molecular biology. 2010, Vol 122, Num 1-3, pp 28-34, issn 0960-0760, 7 p.Article

Discovery and optimization of benzenesulfonanilide derivatives as a novel class of 11β-HSD1 inhibitorsREW, Yosup; DEGRAFFENREID, Michael; XIAO HE et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 11, pp 3786-3790, issn 0960-894X, 5 p.Article

Optimisation of pharmacokinetic properties in a neutral series of 11β-HSD1 inhibitorsSCOTT, James S; GILL, Adrian L; WHITTAMORE, Paul R. O et al.Bioorganic & medicinal chemistry letters (Print). 2012, Vol 22, Num 21, pp 6756-6761, issn 0960-894X, 6 p.Article

5α-Androstane -3β,7α,17β-triol and 5α -androstane -3β,7β,17β-triol as substrates for the human 11β-hydroxysteroid dehydrogenase type 1HENNEBERT, Olivier; LE MEE, Sandrine; PERNELLE, Christine et al.Steroids. 2007, Vol 72, Num 13, pp 855-864, issn 0039-128X, 10 p.Article

Selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic miceALBERTS, P; ENGBLOM, L; EDLING, N et al.Diabetologia (Berlin). 2002, Vol 45, Num 11, pp 1528-1532, issn 0012-186X, 5 p.Article

Hepatic inflammation induced by high-fructose diet is associated with altered 11βHSD1 expression in the liver of Wistar ratsVASILJEVIC, Ana; BURSAC, Biljana; DJORDJEVIC, Ana et al.European journal of nutrition (Print). 2014, Vol 53, Num 6, pp 1393-1402, issn 1436-6207, 10 p.Article

7a-and 7β -hydroxy -epiandrosterone as substrates and inhibitors for the human 11 β-hydroxysteroid dehydrogenase type 1HENNEBERT, Olivier; PERNELLE, Christine; FERROUD, Clotilde et al.Journal of steroid biochemistry and molecular biology. 2007, Vol 105, Num 1-5, pp 159-165, issn 0960-0760, 7 p.Article

Sex steroids and leptin regulate 11β-hydroxysteroid dehydrogenase I and P450 aromatase expressions in human preadipocytes : Sex specificitiesDIEUDONNE, Marie-Noëlle; SAMMARI, Anes; DOS SANTOS, Esther et al.Journal of steroid biochemistry and molecular biology. 2006, Vol 99, Num 4-5, pp 189-196, issn 0960-0760, 8 p.Article

Dietary fructose-related adiposity and glucocorticoid receptor function in visceral adipose tissue of female ratsKOVACEVIC, Sanja; NESTOROV, Jelena; MATIC, Gordana et al.European journal of nutrition (Print). 2014, Vol 53, Num 6, pp 1409-1420, issn 1436-6207, 12 p.Article

L'enzyme 11βHSD1: Une nouvelle cible potentielle pour le traitement du diabète de type 2 et des maladies métaboliques liées à l'obésitéBECK, Emmanuel; SCHEEN, André J.Diabète & obésité. 2013, Vol 8, Num 72, pp 256-258, issn 1957-5238, 3 p.Article

Alternative mechanism for anti-obesity effect of dehydroepiandrosterone: Possible contribution of 11 β-hydroxysteroid dehydrogenase type 1 inhibition in rodent adipose tissueTAGAWA, Noriko; MINAMITANI, Erika; YAMAGUCHI, Yuko et al.Steroids. 2011, Vol 76, Num 14, pp 1546-1553, issn 0039-128X, 8 p.Article

Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1)WU, Shung C; YOON, David; PONTICIELLO, Randolph P et al.Bioorganic & medicinal chemistry letters (Print). 2011, Vol 21, Num 22, pp 6693-6698, issn 0960-894X, 6 p.Article

11β-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissuesBERTHIAUME, Magalie; LAPLANTE, Mathieu; FESTUCCIA, William T et al.American journal of physiology. Endocrinology and metabolism. 2007, Vol 56, Num 4, issn 0193-1849, E1045-E1052Article

The discovery of azepane sulfonamides as potent 11β-HSD1 inhibitorsNEELAMKAVIL, Santhosh F; BOYLE, Craig D; CHACKALAMANNIL, Samuel et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 16, pp 4563-4565, issn 0960-894X, 3 p.Article

The environmental obesogen bisphenol A promotes adipogenesis by increasing the amount of 11β-hydroxysteroid dehydrogenase type 1 in the adipose tissue of childrenWANG, J; SUN, B; HOU, M et al.International journal of obesity. 2013, Vol 37, Num 7, pp 999-1005, issn 0307-0565, 7 p.Article

Tissue-specific dysregulation of hexose-6-phosphate dehydrogenase and glucose-6-phosphate transporter production in db/db mice as a model of type 2 diabetesWANG, Y; NAKAGAWA, Y; LIU, L et al.Diabetologia (Berlin). 2011, Vol 54, Num 2, pp 440-450, issn 0012-186X, 11 p.Article

Inhibition of human and rat 11β-hydroxysteroid dehydrogenases activities by bisphenol AJINGJING GUO; XIAOHUAN YUAN; LI QIU et al.Toxicology letters. 2012, Vol 215, Num 2, pp 126-130, issn 0378-4274, 5 p.Article

Structure-based virtual screening for identification of novel 11β-HSD1 inhibitorsHUAIYUYANG; YU SHEN; JUNHUA CHEN et al.European journal of medicinal chemistry. 2009, Vol 44, Num 3, pp 1167-1171, issn 0223-5234, 5 p.Article

Oleanolic acid derivative NPLC441 potently stimulates glucose transport in 3T3-L1 adipocytes via a multi-target mechanismZHONGHUI LIN; YU ZHANG; YINAN ZHANG et al.Biochemical pharmacology. 2008, Vol 76, Num 10, pp 1251-1262, issn 0006-2952, 12 p.Article

Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitorsXIANGDONG SU; HALEM, Heather A; THOMAS, Mark P et al.Bioorganic & medicinal chemistry. 2012, Vol 20, Num 21, pp 6394-6402, issn 0968-0896, 9 p.Article

Tissue-specific dysregulation of cortisol regeneration by 11βHSD1 in obesity: has it promised too much?STOMBY, Andreas; ANDREW, Ruth; WALKER, Brian R et al.Diabetologia (Berlin). 2014, Vol 57, Num 6, pp 1100-1110, issn 0012-186X, 11 p.Article

11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors as Promising Therapeutic Drugs for Diabetes: Status and DevelopmentGE, R; HUANG, Y; LIANG, G et al.Current medicinal chemistry. 2010, Vol 17, Num 5, pp 412-422, issn 0929-8673, 11 p.Article

Endogenous inhibitors (GALFs) of 11 β-hydroxysteroid dehydrogenase isoforms 1 and 2 : Derivatives of adrenally produced corticosterone and cortisolMORRIS, D. J; LATIF, S. A; HARDY, M. P et al.Journal of steroid biochemistry and molecular biology. 2007, Vol 104, Num 3-5, pp 161-168, issn 0960-0760, 8 p.Article